检测B型尿钠肽对慢性心肾综合征患者诊断和治疗的临床意义被引量：1

Clinic significance of BNP testing in diagnosis and treatment of patients with chronic cardio-renal syndrome

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摘要目的探讨B型尿钠肽(BNP)检测对慢性心肾综合征患者诊断和治疗的临床意义。方法对该院以心脏疾病为基础病的慢性心力衰竭患者54例的临床资料进行回顾性分析,并按照患者入院时血肌肝(Scr)是否≥133 mmol/L分为单纯慢性心力衰竭组26例和慢性心肾综合征组28例。结果慢性心肾综合征组的BNP的水平[(1321.5±93.88)pg/L]明显高于单纯慢性心力衰竭组[(865.4±120.32)pg/L](P<0.05)。两组患者的BNP水平均与左室舒张末期内径(LVEDD)呈正相关,与左室射血分数(LVEF)呈负相关(P<0.05)。结论 BNP检测对慢性心肾综合征患者心功能的诊断、病情的判断、指导治疗以及评估预后有重要意义。 Objective To understand the clinical significance of BNP in patients with chronic cardio-renal syndrome. Methods The clinical data of 54 chronic heart failure patients with heart disease as underlying disease in the 416 Hospital of Nuclear Industry was retrospectively analyzed. Twenty-six hospitalized patients with simple chronic heart failure（ simple heart failure group）, and 28 hospitalized patients with chronic cardio-renal syndrome（ cardio-re- nal syndrome group） were retrospectively analyzed. Results The BNP level of chronic cardio-renal syndrome group was significantly higher than that of simple heart failure group （ 1321.5 ±93.88） vs （865.4 ±120. 32）pg/L, P 〈 0.05 ） ; The BNP levels of two groups were positively related to the LVEDD and negative related to LVEF （ P 〈 0. 05）. Conclusion BNP can be as applied to cardiac function diagnosis, severity evaluation, therapy guide and prognosis evaluation in patients with chronic cardio-renal syndrome.

作者尹锐

机构地区核工业四一六医院心内科

出处《中国临床新医学》 2013年第10期980-982,共3页 CHINESE JOURNAL OF NEW CLINICAL MEDICINE

关键词 B型尿钠肽(BNP) 心肾综合征慢性心力衰竭 Brain natriuretic peptide Cardio-renal syndrome Cltronie heart failure

分类号 R542.2 [医药卫生—心血管疾病]

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