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阿立哌唑结合认知行为疗法对精神分裂症患者疗效和生活质量的影响 被引量：8

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摘要 目的观察阿立哌唑结合认知行为疗法对精神分裂症患者疗效和生活质量的影响。方法选择2011年10月至2012年10月80例精神分裂症患者,采用随机数字表法将患者随机均分为观察组和对照组,疗程均为12周。对照组给予阿立哌唑10～30mg/d口服,2次/天,观察组在对照组的基础上结合认知行为疗法(寻找错误认知,论证、分析和重建合理认知,强化重建认知)。观察治疗前、治疗12周后患者的简明精神病评定量表(BPRS)、阳性症状评定量表(SAPS)和阴性症状评定量表(SANS)评分、治疗时出现的症状量表(TESS)疗效和生活质量量表(SQLS)变化。结果治疗前,两组BPRS、SAPS、SANS评分差异无统计学意义(P>0.05);治疗12周后,两组各项评分显著降低(P<0.05),但观察组降低比对照组明显(P<0.05)。观察组TESS的总有效率为95.00%,显著高于对照组的80.00%(P<0.05)。治疗后两组SQLS各项评分均明显减少,但观察组减少比对照组更明显(P<0.05)。结论阿立哌唑结合认知行为疗法可明显提高精神分裂症患者的疗效,改善生活质量。
作者 严叶良 陆晋军
机构地区 江苏省江阴市第三人民医院精神科
出处 《检验医学与临床》 CAS 2013年第20期2716-2718,共3页 Laboratory Medicine and Clinic
关键词 精神分裂症 阿立哌唑 认知行为疗法 疗效 生活质量
分类号 R749.3 [医药卫生—神经病学与精神病学]
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参考文献11

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二级参考文献13

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共引文献64

同被引文献100

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检验医学与临床
2013年 第20期

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