2012年陕西省耐药监测网ICU与非ICU病房鲍曼不动杆菌耐药监测结果

The comparation of the antibiotics-resistant rate of acinetobacter baumannii isolated between ICU and other wards from Shanxi province antibacterial resistance investigation net 2012

目的了解2012年度陕西省耐药监测网入网医院ICU病区患者与非ICU病区患者鲍曼不动杆菌耐药性整体差异。方法收集2012年陕西省耐药监测网入网医院上报ICU和非ICU住院患者临床分离鲍曼不动杆菌的相关数据,根据美国实验室与临床标准化研究所(CLSI)2012版标准,用WHONET 5.6软件进行数据分析。结果共获得临床分离鲍曼不动杆菌2 824株,其中ICU病房分离480株,占17.0%;非ICU病房分离2 344株,占83.0%;ICU痰标本比例高于非ICU(P<0.05);药敏结果显示ICU与非ICU来源的鲍曼不动杆菌仅对多黏菌素敏感性较好;来源于非ICU的菌株对米诺环素耐药性强于ICU菌株(P<0.01);头孢哌酮/舒巴坦在内的其他8种抗菌药物,来源于ICU的菌株耐药性均强于非ICU菌株,二者差异有统计学意义(P<0.01)。结论了解不同来源鲍曼不动杆菌的耐药性,合理使用抗菌药物和加强医院感染管理是减少不动杆菌多耐药菌株在医院感染的主要途径。

Objective To study the difference of the antibiotic susceptibility of Acinetobacter baumannii isolated from ICU and other wards from Shanxi province antibacterial resistance investigation net 2012.Methods Reviewed the data of the antibiotic susceptibility test of Acinetobacter baumannii isolated from ICU and other wards from Shanxi province antibacterial resistance investigation net 2012.Data were analyzed by WHONET 5.6.Results The antibiotic resistant rate of PB was similar in ICU and nonICU（P＆gt;0.05）;The antibiotic resistant rate of MH from non-ICU was significant higher than those from ICU（P＆lt;0.01）.The others antibiotic resistant rate of Acinetobacter baumannii isolated from ICU were significant higher than those from the other wards（P＆lt;0.01）.Conclusion It is very important to use antibiotics rationally in clinic and to manage strictly to decrease the occurrence rate of multi-antibiotics-resistant strain of Acinetobacter baumannii.