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微小RNA与类风湿关节炎 被引量:2

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摘要 微小RNA(microRNA,miRNA)是一种起转录后负调控的分子,参与生命过程中一系列重要进程,包括发育进程、造血过程、器官形成、凋亡、细胞增殖和肿瘤的发生。作为一组新的潜在的疾病诊断和治疗的靶分子,已成为了生物医学研究的前沿热点。生物信息学预测显示,在哺乳动物中,miRNA虽然占不到2%蛋白编码基因,却可以调控1/3的mRNAs。miRNA可以调控人类60%的蛋白编码基因,表明其功能强大[1]。
出处 《国际检验医学杂志》 CAS 2013年第20期2711-2712,共2页 International Journal of Laboratory Medicine
基金 广东省自然科学基金资助项目(S2011010004750)
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参考文献12

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二级参考文献30

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