摘要
NR5A2属于是核受体超家族,是有配体激活的转录因子,它还属于NR5A亚家族,是一孤儿受体,也是肝受体同系物。一方面,在动物的肝脏、胰腺、肠及卵巢等脏器中NR5A2得到表达,尤其是在卵巢中为高表达;另一方面,NR5A2在动物胚胎发育及分化、体细胞编程、胆固醇或胆汁酸代谢、类固醇激素生成和生殖活动等方面发挥重要作用。
NR5A2 belonging to the nuclear receptor superfamily, is a ligand-activat-ed transcription factors, it is NR5A subfamily, is a orphan receptor, is the liver receptor homologue. On the one hand, in the animals＇ liver, pancreas, intestines and other organs in NR5A2 ovary was expressed, particularly in the ovary to get as high expression; On the other hand, NR5A2 in animal embryonic development and differentia-tion, somatic cell programming, cholesterol metabolism or metabolism of bile acids, steroid hormone production and reproductive activities play an important role.
出处
《现代畜牧兽医》
2013年第10期12-16,共5页
Modern Journal of Animal Husbandry and Veterinary Medicine
