摘要
目的观察促红细胞生成素(EPO)与胃癌患者化疗疗效及依从性的相关性。方法将40例局部晚期胃癌并轻度贫血患者均分为2组,每组20例,治疗组化疗同时给予EPO,开始剂量为150 U/kg,每周3次,持续观察3周期化疗。对照组单纯化疗。结果整个治疗过程中,治疗组血红蛋白(Hb)、红细胞(RBC)、网织红细胞(Ret)、红细胞压积(HCT)水平高于对照组,治疗组近期疗效明显高于对照组(P<0.05)。结论 EPO能明显改善胃癌贫血患者的血液学指标,提高化疗近期疗效及化疗依从性。
Objective To analyze the efficacy and dependability of the erythropoietin to patients with gastric cancer. Methods 40 patients with gastric cancer were enrolled as research group and control group at random,each group were 20 cases. Patients of the research group were using chemotherapy and erythropoietin 150U/kg,3 times every week. The control group were by chemotherapy merely. Results Comparing with the control group,the hemoglobin,red blood cell,packed cell volume of the pa- tients in the research group were much higher during the therapy course, and there were differences in the recent efficacy between the two groups （P〈0.05）. Conclusion Erythropoietin （EPO） had a good effect on patients with gastric cancer,it can improve the hematology index of such patients, and also improve the curative effect and dependability.
出处
《江西医药》
CAS
2013年第9期774-777,共4页
Jiangxi Medical Journal
基金
江西省卫生厅课题(20063066)
关键词
促红素
胃癌
化疗
疗效
依从性
Erythropoietin（EPO）
Gastric cancer
Chemotherapy
Efficacy
Dependability
