酶促开环聚合及原子转移自由基聚合串联法合成聚碳酸酯-聚苯乙烯二嵌段聚合物

Combining Block Polymer of Polycarbonate-Polystyrene by Tandem Method of Enzymatic Ring-Opening Polymerization and Atom Transfer Radical Polymerization

以单苄撑缩季戍四醇为前体,合成了一端为α-溴代丙酸酯,一端为羟基的双官能引发剂。以此引发剂,先引发脂肪酶催化的甲基环碳酸酯开环聚合(ROP)反应,再进一步在CuCl/2,2’-bpy催化下于同一反应器中串联引发苯乙烯的原子转移自由基聚合(ATRP)。利用温度的变化,在同一反应器中进行了两种不同的反应。对不同反应条件下所得聚合产物进行了GPC,1HNMR,13CNMR测试。

This work is directed towards developing a new method for the synthesis of block copolymers combining enzymatic ring opening polymerization （ ROP） and atom transfer radical polymerization （ ATRP） , by using a bifunctional initiator gained from the combining a primary alcohol and α-bromoester .The ROP of trimethylene carbonate （ TMC） is carried out in bulk by using No-vozym-435and ATRP of styrene catalyzed by CuCl/2,2’-Dipyridyl.Block copolymers comprising poly （TMC） and poly（styrene） block are obtained in two consecutive polymerization steps and in a one-pot cascade approach without intermediate transformation . The polymers obtained in different conditions are analyzed by 1 HNMR, 13 CNMR and GPC.