摘要
作为高通量筛选系统的核心,筛选模型在研究深入与技术进步的推动下已得到较大发展与广泛应用。文章从分子、细胞和动物水平三个层面介绍高通量药物筛选模型的研究状况及应用,并对其优缺点与相关机制进行阐述。
As the core of high throughput screening systems, screening models have enjoyed remarkable development and wider application driven by intensive studies and technology advancement. Discussed in this paper are the latest progress in molecule, cell and animal based models of high throughput screening and their recent applications in drug screening, as well as their pros and cons and related theories.
出处
《上海交通大学学报(医学版)》
CAS
CSCD
北大核心
2013年第10期1415-1419,共5页
Journal of Shanghai Jiao tong University:Medical Science
关键词
高通量筛选
药物筛选
筛选模型
high throughput screening
drug screening
models