摘要
通过大、小鼠的急性毒性试验和大鼠蓄积毒性试验及遗传毒性试验表明，康脂口服液的ＬＤ５０大于１０．００ｇ／ｋｇ．ｂｗ，实属无毒物质；蓄积毒性试验表明，本品蓄积系数Ｋ＞５，为弱蓄积；遗传毒性试验得知，Ａｍｅｓ试验无遗传毒性，对小鼠骨髓嗜多染红细胞微核及小鼠精子畸形试验也均未产生影响，说明本品长期服用比较安全。
Acute toxicity experiments on rats and mice, and store up toxicity and hereditary toxicity experiments on rats were done. The results showed that LD50 of 'Healthy Blood Fat Oral Liquid' was over 10.00g/kg. bw. It belongs to non-toxic material. Store up toxicity experiment showed that the store up coefficient of the product is K>5 and belongs to weak store up. Hereditary toxicity experiment also suggested that Ames Experiment had no hereditary toxic. There were no effects towards mi- cronucleus of marrow polychromatophilic erythroblast and sperm malformation experiments of mice. These suggestal that the product is safety for a long-term taking.
出处
《微生物学杂志》
CAS
CSCD
2000年第4期5-6,10,共3页
Journal of Microbiology
关键词
康脂口服液
急性毒性
蓄积毒性
遗传毒性
blood fat
acute tokicity
store up toxicity
Ames experiment
sperm malformation
safety
