儿童交替性偏瘫一例

One case of alternating hemiplegia of childhood

目的了解儿童交替性偏瘫(AHC)的诊断及治疗方法的合理选择。方法介绍我院收治的1例难治的儿童交替性偏瘫患儿的临床特点,检索国内外10年内的相关文献。结果本病的临床特点为反复发作性的偏瘫,睡眠后缓解,可有其他发作性症状,如发作性肌张力障碍、眼球运动异常和认知障碍等。氟桂利嗪是最常用的药物,托吡酯片、阿立哌唑也可用于治疗本病。结论本病是一种罕见的神经系统发作性疾病,临床表现多样,容易误诊,目前没有标准的治疗方法。

Objective Alternating hemiplegia of childhood was an entity of uncertain etiology. Methods This paroxysmal disease with progressive course is characterized by repeated episodes of hemiplegia that alternates its location. Results These episodes are usually aborted during sleep. Paroxysmal eye movements, cognitive impairment and autonomic disorders, can also be seen. Due to its progressive course and bad prognosis, it turns out to be important for the generalist physician to be aware of this entity, thus facilitating an early diagnosis and avoiding empiric pharmacologic ineffective treatments. Conclusion We present the case of a eleven year-old girl with alternating hemiplegia of childhood, show imaging of this disease and make a brief review of the literature.