摘要
目的探讨良恶性腹水中CD8+CD28-T细胞表达水平及意义,以便为良恶性腹水的鉴别诊断提供新的思路和方法。方法采用流式细胞仪检测24例肝硬化性腹水、20例结核性腹水、28例恶性腹水中CD8+CD28-T细胞表达水平。结果恶性腹水组CD8+CD28-T细胞表达水平为(24.75±4.09)%,明显高于结核性腹水组(13.83±2.38)%及肝硬化性腹水组(16.15±1.49)%,后两组比较差异有统计学意义(P<0.05)。结论 CD8+CD28-T细胞表达水平在良恶性腹水中存在显著差异,可作为判定良恶性腹水的辅助诊断指标。
Objective To study the expression new technology for the early diagnosis of malignan of CD8 + CD28 - T cells in benign and malignant ascites and provide a t ascites. Methods Flow cytometry was used to test the levels of CD8 + CD28-T cells in hepatocirrhosis ascites (n = 24), tuberculous ascites (n = 20) and malignant ascites (n = 28). Results The percent of CD8 + CD28 - T cells in malignant ascites group (24.75 ± 4.09) % was higher than that in hep- atocirrhosis ascites group ( 16.15 ± 1.49) % and tuberculous ascites group ( 13.83 ± 2.38) % , there was statistically significant difference between hepatocirrhosis ascites and tuberculous ascites groups (P 〈 0.05). Conclusion CD8 + CD28-T ceils is significantly different between malignant ascites hepatocirrhosis ascites and tuberculous ascites, they could be used to distinguish malignant ascites from hepatocirrhosis and tuberculous.
出处
《胃肠病学和肝病学杂志》
CAS
2013年第10期1034-1036,共3页
Chinese Journal of Gastroenterology and Hepatology