犬小孢子菌致皮肤癣菌病162例回顾分析

Microsporum canis infection: analysis of 162 cases

目的回顾分析2011—2012年期间上海地区犬小孢子菌致病的临床特征。方法依据真菌学检查确诊162例为犬小孢子菌感染，分析患者资料、病程、动物接触史、家庭成员感染情况、用药史及治疗情况。结果15岁以下的儿童患者（≤15岁）39例，平均年龄6．3岁，男16例，女23例，男女比例为0．70：1，头癣21例（85．7％为白癣）、面癣11例、体癣7例。成人患者（〉15岁）123例，平均年龄36．6岁，男20例，女103例，男女比例为0．19：1，体癣91例、面癣28例、头癣4例。家庭成员同时患病16例（8对）。139例（85．8％）有确切的动物接触史，宠物为可能的传染源（猫、犬等）。结论犬小孢子菌引起的皮肤癣菌病在年龄性别分布和临床类型上具有特殊性：儿童患者性别差异不明显，以头癣为主；而成人患者以体癣为主，21—40岁感染的患者最多见，女性患者明显多于男性，暴露处是最常见的感染部位。经规范治疗，所有患者的犬小孢子菌均清除治愈。对家里的宠物也要同时治疗，以消灭传染源。

Objective Microsporum canis is one of the common causative agents of dermatophytosis. This paper analyzed 162 patients infected with M. canis who attended outpatient clinic during 2011 to 2012. Methods M. canis infections were diagnosed by mycological examinations. Analyze basic information, medicine histories, clinical characteristics and treatment of these patients. Re- suits There were 39 cases in children under the age of 15, the ratio of male to female patients was 0.7： 1, tinea capitis was the most common form. There were 123 cases in adult patients, the ratio of male to female patients was 0.19： 1, tinea corporis was the most common form. Family members infected M. eanis at the same time in 16 cases （8 couples）. There were 139 cases of exactly an- imal contact history （ 85.8% ）, pet was a possible source of infection （ cats or dogs）. Conclusion Dermatomycosis caused by M. canis is special in the age and sex distribution and clinical types. After standard therapy, all patients with M. canis were fully healed. The pets should be treated at the same time, in order to eliminate the source of infection.