急性前葡萄膜炎215例临床分析

Clinical analysis of acute anterior uveitis in 215 cases

目的:分析并探讨急性前葡萄膜炎的病因、治疗效果、复发率及预后等问题。方法:对近5a在奉化人民医院眼科诊治的215例急性前葡萄膜炎进行详细病史采集、临床检查及各项辅助检查,观察其治疗效果及复发情况,对其病因、预后及复发率进行分析。结果:查找到病因者85例(39.5%),病因位列前三的是外伤或手术后急性前葡萄膜炎、病毒性前葡萄膜炎及青光眼睫状体炎综合征。治疗后最佳矫正视力≥1.0者153例(71.2%),0.5≤视力<1.0者55例(25.6%),0.3≤视力<0.5者4例(1.9%),0.05≤视力<0.3者2例(0.9%),视力<0.05者1例(0.5%)。所有病例在6mo以上的随访过程中,4～6mo内复发者4例(1.9%),7～12mo复发者7例(3.2%),13～24mo复发者10例(4.7%),25～60mo复发者3例(1.4%)。结论:急性前葡萄膜炎病因复杂,多为特发性,治疗后视力预后较好,但复发率高,反复发作影响视力,故应了解其复发特点,重预防,早治疗。

AIM： To analyze the etiology, therapeutic effects, risk of relapse and prognosis of acute anterior uveitis. MEHTODS： Medical history of 215 patients with acute anterior uveitis who underwent treatment in Department of Ophthalmology, People＇s Hospital of Fenghua was collected, together with results of clinical examinations and auxiliary examinations. The data were studied in terms of therapeutic effects, etiological factors, prognosis and relapse rate. ~ RESULTS： In 85 cases （~39. 5%）, the cause was identified, and among the among the most frequent causes were traumatic or surgical injury, viral infection and glaucomatocyclitic crisis. After treatment, the best corrected visual acuity was no less than 1.0 in 153 cases （71.2%）, between 0.5 and 1.0 in 55 cases （25.6%）, between 0.3 and 0.5 in 4 cases （1.9%）, between 0.05 and 0.3 in 2 cases （0. 9%）, and less than 0. 05 in 1 case （0.5%）. During the follow-up of more than 6 months, relapse occurred in 4 cases （1.9%） during 4-6 months, in 7 cases （3.2%） during 7-12 months, in 10 cases （4.7%） during 13-24 months, and in 3 cases （1.4%） during 25-60 months. ~ CONCLUSION： The etiology of acute anterior uveitis is complicated and mostly idiopathic. Vision prognosis is good after treatment, but therelapse rate is high and can cause visual impairment, so better understanding should be gained of its relapse and its prevention and early treatment should be emphasized.