摘要
目的 观察痰热清联合头孢噻肟治疗慢性支气管炎急性发作的临床疗效,并探讨其疗效机制.方法 将88例符合入组标准的慢性支气管炎急性发作患者随机分为对照组44例和观察组44例,两组均给予支持、对症、解痉、止咳、祛痰等对症治疗,对照组再静脉点滴头孢噻肟钠注射液4~6g,使用250mL生理盐水稀释,每分钟40~60滴,观察组在对照组的基础上,再静脉点滴痰热清注射液20mL,使用250mL生理盐水稀释,每分钟40~60滴,两组均治疗10d,治疗前后观察患者咳痰、咳嗽、发热、肺部体征症状改善情况,记录症状改善时间,评价患者总体临床疗效及症状疗效差异.结果 两组的临床总有效率分别为93.18%和75.00%,差异具有统计学意义.结论 痰热清联合头孢噻肟治疗慢性支气管炎急性发作临床疗效确切,对患者咳嗽、咳痰、发热效果显著,且安全性好,可作为慢性支气管炎急性发作治疗理想方法.
OBJECTIVE To observe the effect of the method containing Tanreqing injection and Cefotaxime in the treatment of acute exacerbation of chronic bronchitis, and to explore the mechanism of Tanreqing. METHODS 88 chronic bronchitis acute exacerbation patients met inclusion criteria were randomly divided into, 44 cases of the control group and 44 cases of observation group. Both groups were given the support for the symptomatic treatmem o~' symptomatic, antispasmodic, cough, expectorant, the Control group were given intravenous Cefotaxime sodium inje,-tion 4 ~ 6g, The observation group were given Tanreqing injection 29mL on the basis of the control group. Both group ]md been treated for 10d. The sputum,cough, fever,improvement of symptoms of pulmonary signs, and record the time of symptoms improved were observed, The overall clinical efficacy and symptom differences in efficacy were evahm- ted. RESULTS The total effective rate of observation group was 93.18%, the control group was 75.00%, the ob- servation group was significantly higher than the control, the difference was statistically significant. CONCLUSION The method containing Tanreqing injection and Cefotaxime have exact effect, can relieve cough, expectoration, fever, have good security, can be used as a treatment ideal way to chronic bronchitis in the treatment of acute exacerba- tion of chronic bronchitis.
出处
《海峡药学》
2013年第10期94-96,共3页
Strait Pharmaceutical Journal
关键词
痰热清
头孢噻肟
慢性支气管炎急性发作
临床疗效
Tanreqing
Cefotaxime
Acute exacerbation of chronic bronchitis
Clinical efficacy