青年脑卒中患者复发危险因素的研究

Study on risk factors for relapse of stroke in young people

目的探讨青年脑卒中患者复发的相关危险因素。方法选择本院2006—2011年收治的45岁以下脑卒中住院患者共436名为研究对象,随访6个月、1年、2年,收集患者的基本情况、临床相关资料以及相关疾病史,采用IBM SPSS statistics 20.0软件进行Logistic回归分析,探讨青年脑卒中患者复发的危险因素。结果接受随访的患者中,有89例患者发生复发,复发率为20.41%。通过对青年脑卒中患者复发的单因素分析和多因素Logistic回归分析,结果显示年龄、情绪波动情况、婚姻状况、熬夜、经常上网、体育锻炼、血脂水平、血糖水平、血压水平、心脏病史、饮酒史、脑卒中家族史、TIA史共计13个因素与青年脑卒中复发相关(P<0.05)。体育锻炼、已婚为青年脑卒中复发的保护因素。结论青年脑卒中复发与多种因素相关,但与中老年脑卒中复发的影响因素有所不同。情绪剧烈波动、经常熬夜、经常上网、高血脂、高血糖、高血压、心脏病史、饮酒史、脑卒中家族史是青年脑卒中复发的危险因素,经常进行体育锻炼和已婚状况能够一定程度上预防青年脑卒中复发。

Objective To explore risk factors for relapse of stroke in young people. Methods A total of 436 stroke patients less than 45 years old were enrolled to carry out a risk factors analy- sis. All the patients were followed up for 6 months, 1 year and 2 years to collect the data of condi- tion, clinical relevant information and related disease history. The data was statistically analyzed by logistic regression model in IBM SPSS statistics 20.0 to explore the risk factors for relapse of stroke in young people. Results Eighty-nine patients relapsed, and the relapse rate was 20.41%. The u- nivariate analysis results showed that 13 factors were associated with relapse of stroke in young peo- ple, including age, mood swings, physical exercise, staying-up late, online duration, marital sta- tus, blood lipid levels, blood glucose level, blood pressure, heart diseases history, drinking history, family history of stroke, and T1A history（P〈0.05）. Physical exercise and being married were pro- tective factors for relapse of stroke in young people. Conclusion A variety of factors are associated with relapse of stroke in young people, which is different from that in elderly stroke relapse. Emo- tional fluctuation, staying-up late, frequent surfing the Internet, hyperlipidemia, hyperglycemia, hypertension, heart diseases history, drinking history and family history of stroke are risk factors for relapse d stroke in young people. Regular physical exercise and being married can help young people to prevent relapse of stroke to some extent.