期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

瑞舒伐他汀对冠状动脉慢血流患者hs-CRP,TNF-α,IL-6的影响 被引量：4

下载PDF
导出
摘要 目的研究瑞舒伐他汀对冠状动脉慢血流患者的临床疗效及对hs-CRP,TNF-α,IL-6的影响。方法选冠状动脉慢血流患者80例随机分为治疗和对照组,对照组(40例)予常规治疗,治疗组(40例)在常规治疗基础上加用瑞舒伐他汀20mg/d,治疗2周后观察两组临床疗效及hs-CRP,TNF-α,IL-6水平。结果治疗组患者显效率为50.00%明显高于对照组10.00%,并且有效率为70.00%明显高于对照组的40.00%,差异有明显的统计学意义(P<0.01),并且两组患者TNF-α、IL-6、hs-CRP两组治疗后水平均有所下降,其中治疗组下降水平更为明显,两组患者治疗后TNF-α、IL-6、hs-CRP水平差异均有明显的统计学意义(P<0.05)。结论瑞舒伐他汀可以通过改善对冠状动脉慢血流患者炎性反应,从而明显提高临床治疗效果。
作者 王汝意
机构地区 滨州市中心医院心血管内科二病区
出处 《中国医药指南》 2013年第27期103-104,共2页 Guide of China Medicine
关键词 冠状动脉慢血流现象 瑞舒伐他汀 HS-CRP TNF—α IL-6
分类号 R541 [医药卫生—心血管疾病]
  • 相关文献

参考文献7

  • 1Fragasso G5Maranta F.The light of inflammation iii the darknessof the coronary slow flow phenomenon[J].Anadolu KardiyolDerg,2013,13(1):45-47.
  • 2Nie SP5Wang X1Geng LL,et.al.Anatomic properties of coronaryarteries are correlated to the corrected thrombolysis in myocardialinfarction frame count in the coronary slow flow phenomenon[J].Coron Artery Dis,2012,23(3):174-180.
  • 3Saya SjHennebry TAjLozano P,et.al.Coronary slow flow phenomenonand risk for sudden cardiac death due to ventricular arrhythmias:a case report and review of literature[J].Clin Cardiol,2008,31(8):352-355.
  • 4Beltrame JFjTumer SP5Leslie SL,et al.The angiographic andclinical benefits of mibefradil in the coronary slow phenomenon[J].J Am Coll Cardiol,2004,44(1):57-62.
  • 5SayaS1HennebryTA,LozanoP,et.al.Coronary slow flow phenom-enon and risk for sudden cardiac death due to ventriculararrhyth-mias:a case report and review of literature[J].Clin Cardiol,2008,31(8):352-355.
  • 6Camsari AjOzcan T,Ozer C,et al.Carotid artery intima-mediathickness correlates with intravascular ultrasound parameters inpatients with slow coronary flow[J].Atherosclerosis,2008,200(2):310-314.
  • 7赵睿,杨蕊.超敏C反应蛋白与冠状动脉慢血流现象的关系[J].西部医学,2010,22(7):1198-1200. 被引量：5

二级参考文献15

  • 1张邢炜,葛均波,潘浩,高炎,李佩璋,王宁夫,周亮,杨建敏.C反应蛋白对人内皮细胞凋亡相关基因Bcl-2／Bax表达的影响[J].中华心血管病杂志,2006,34(7):639-642. 被引量：6
  • 2Tambe AA, Demany MA, Zimmerman HA, etal. Angina pectoris and slow flow velocity of dye in coronary arteries:a new angiographic finding [J] . Am Heart J, 1972, 84(1):66.
  • 3Beltrame JF, Limaye SB, Horowitz JD. The coronary slow flow phenomenon-a new coronary mierovascular disorder [J]. Cardiology, 2002, 97(4):197.
  • 4Pekdemir H, Cin VG, Cieek D, et al. Slow coronary flow may be a sign of diffuse atherosclerosis. Contribution of FFR and IVUS [J]. Acta Cardiol,2004,59(2), 127.
  • 5Li JJ, Qin XW, Li ZC, et al. Increased plasma C-reactive protein and interleukin-6 concentrations in patients with slow coronary flow [J]. Clin Chim Acta, 2007, 385(1-2) :43.
  • 6Ridker PM, Stampfer MJ, Rifai N. Novel risk factors for systemic atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein ( a), and standard cholesterol screening as predictors of peripheral arterial disease[J]. JAMA, 2001, 285(19): 2481.
  • 7Gibson CM, Cannon CP, Daley WL, et al. TIMI frame count: a quantitative method of assessing coronary artery flow[J]. Circulation, 1996, 93(5) :879.
  • 8Patel VB, Robbins MA, Topoi EJ. C-reactive protein: a'golden marker' for inflammation and coronary artery disease[J]. Cleve ClinJ Med, 2001, 68(6)1521.
  • 9Rifai N, Ridker PM. High-sensitivity C-reactive protein: a novel and promising marker of coronary heart disease [J]. Clin Chem, 2001, 47(3) :403.
  • 10Chapidze G, Dolidze N, Enquobahrie DA, et al. Metabolic syndrome and C-reactive protein among cardiology patients[J]. Arch Med Res,2007,38(7):783.

共引文献4

同被引文献13

引证文献4

二级引证文献17

中国医药指南
2013年 第27期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部