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重型脑损伤的临床探析

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摘要 目的探究重型脑损伤临床治疗方法以及麻醉方式。方法选取2010年8月至2012年8月在我院就诊的60例重型颅脑损伤患者,采用随机的方法将其分为对照组和观察组,每组30例。两组患者均采用相同的药物进行麻醉诱导,其中对照组患者采用丙泊酚维持麻醉,观察组患者采用芬太尼+丙泊酚维持麻醉。观察两组患者的生命体征以及循环状况,对相应的并发症采取有效的预防措施。结果行重型颅脑损伤手术后,观察组因肝脾破裂导致出血休克,抢救无效死亡1例,由于脑组织不可逆的损伤导致死亡1例,观察组总有效率为93.3%;对照组患者在手术中无1例死亡,术后由于脑部严重的并发症死亡2例,因肺部严重感染合并多器官功能障碍综合症(MODS)而导致死亡3例,对照组总有效率为83.3%。观察组总有效率明显高于对照组,存在显著差异,具有统计学意义(P<0.05)。结论行重型颅脑损伤手术,在采用相同的药物进行麻醉诱导条件下,相比较丙泊酚(propofol)维持麻醉,使用芬太尼+丙泊酚维持麻醉能够取得更好的临床效果。
作者 聂云辉
出处 《中国医药指南》 2013年第29期330-331,共2页 Guide of China Medicine
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