磁共振扩散加权成像与胼胝体梗死临床相关性分析

Clinical Analysis of Correlation between Diffusion-Weighted MR Imaging and Corpus Callosum Infarction

目的探讨磁共振扩散加权成像对胼胝体梗死诊断价值以及胼胝体梗死危险因素、临床症状和预后相关性分析。方法分析27例胼胝体梗死患者的临床资料与磁共振扩散加权成像信号变化的相关性。结果对急性胼胝体梗死的诊断,磁共振扩散加权成像比常规T2WI、T1WI、T2WI-FLAIR敏感。动脉硬化及颈内斑块形成是胼胝体梗死的主要危险因素。胼胝体梗死主要发生于胼胝体膝、体部。以下肢为主的瘫痪、智能障碍、失语、小便失禁是胼胝体梗死的主要表现。胼胝体梗死随发病时间推移治疗有效率逐步下降,差异有统计学意义(P<0.05)。结论磁共振扩散加权成像是诊断急性胼胝体梗死的有效方法,早期诊断及治疗对急性胼胝体梗死预后至关重要。

Objective To investigate the efficacy of diffusion-weighted MR imaging（DWI） in the diagnosis of corpus callo-sum infarction, and explore the risk factors, clinical manifestations, prognosis of corpus callosum infarction by DWI. Methods The correlation between diffusion-weighted MR Imaging signal and the clinical data of 27 cases of corpus callosum infarction were analyzed. Results The diffusion weighted imaging sequences had a higher positive rate in phase of the corpus eallosum infarc- tion, and was more sensitive than conventional T2WI ,T1WI and T2WI-FLAIR. The carotid atherosclerosis and plaque formation was the mainly risk factors of corpus callosum infarction. The infarction commonly occurred to the knee and body of corpus callo-sum. The major clinical manifestations of corpus eallosum infarction were the reduced muscle strength of lower limbs, mental retar-dation, aphasia and urinary incontinence. The therapeutic efficiency decreased with the pathogenesis of time of corpus callosum in-farction, and the difference was statistically significant （ P 〈 0.05 ）. Conclusion DWI is an effective method for the diagnosis of the corpus callosum infarction. The early diagnosis and treatment can improve the prognosis of patients.