摘要
目的:评价注射用兰索拉唑在十二指肠溃疡并出血中的临床疗效。方法:采用随机、单盲、阳性药物(奥美拉唑)平行对照多中心临床试验的研究方法对2009年7月至2010年8月间十二指肠溃疡并出血住院患者240例进行疗效分析。结果:经过治疗后,两组治疗十二指肠溃疡并出血的疗效、止血时间及止血率、不良反应发生率均无明显统计学差异。结论:注射用兰索拉唑治疗十二指肠溃疡并出血疗效确切,不良反应少,值得临床推广使用。
Objectives:To evaluate the clinical effect of Lansoprazole on duodenal bulb ulcer bleeding.Methods:Based on the randomized,single-blind,positive-drug parallel-controlled method of multicenter clinical trial,240patients with duodenal bulb ulcer bleeding from July 2009to August 2010were randomly divided into the Lansoprazole group(120)and the omeprazole group(120).Results:There was no significantly statistical difference concerning effect,hemostasis time and rate, and the incidence rate of adverse reactions in the two groups.Conclusion:Lansoprazole is effective on duodenal bulb ulcer bleeding with less adverse reactions.It is worthy of clinical use.
关键词
兰索拉唑
十二指肠溃疡
出血
疗效
Lansoprazole
duodenal bulb ulcer
bleeding
effective
