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经颅多普勒在急性脑梗死静脉溶栓治疗中的应用观察 被引量:6

TCD observation of thrombolytic therapy in acute cerebral infarction
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摘要 目的应用经颅多普勒(TCD)监测急性脑梗死静脉溶栓治疗前后血流的变化。方法对43例急性脑梗死患者,在治疗前及溶栓治疗开始进行TCD监测并且持续2 h,同时评价静脉溶栓前后的NIHSS评分。结果不同残留血流级别患者中血管再通率有显著性差异,随残留血流信号的改善,NIHSS评分下降。结论 TCD在急性脑梗死静脉溶栓时能及时了解血管再通情况,其血流改善与患者预后密切相关。 Objective Transcranial Doppler (TCD) monitoring changes in blood flow after intravenous thrombolysis treatment in acute cerebral infarction. Methods 43 cases of acute cerebral infarction, started and continued 2 h TCD monitoring before and after thrombolytic therapy, and to evaluate the NIHSS scores before and after intravenous thrombolytic therapy. Results Different residual blood levels in patients with vascular re- canalization rate had significant difference, with the residual signal improvement, NIHSS score decreased. Con. elusion TCD after intravenous thrombolysis in acute cerebral infarction timely understanding of vascular reca- nalization, the improvement of blood flow and prognosis.
出处 《中国现代药物应用》 2013年第20期13-14,共2页 Chinese Journal of Modern Drug Application
关键词 经颅多普勒 静脉溶栓 血栓溶解 Transcranial Doppler Intravenous thrombolytic therapy Thrombolysis
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  • 1Demchuk AM, Burgin WS, Christou L, et al. Thrombolysis in brain ischemia (TIBI) transcranial Doppler flow grades predict clinical severity, early recovery, and mortality in patients treated with in- travenous tissue plasminogen activator. Stroke; a Journal of Cere- bral Circulation, 2001,32( 1 ) : 89-93.
  • 2Burgin WS, Malkoff M, Felberg RA, et al. Transcranial doppler ul- trasound criteria for recanalization after thrombolysis for middle cer- ebral artery stroke. Stroke. a Journal of Cerebral Circulation, 2000,31(5) : 1128-1132.
  • 3Alexandrov AV, Burgin WS, Demchuk AM, et al, Speed of intracra- nial clot lysis with intravenous tissue plasminogen activator therapy : sonographie classification and short-term improvement. Circula- tion, 2001, 103(24): 2897-2902.

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