纳米银抗菌凝胶联合重组人表皮细胞生长因子治疗压疮创面34例疗效分析

Clinical analysis of nanometer silver antibacterial gel combined with recombinant human epidermal growth factor in the treatment of 34 cases of bedsore wound

目的 探讨纳米银抗菌凝胶联合重组人表皮细胞生长因子（rhEGF）在治疗压疮创面中的应用价值.方法 将我院2009年9月至2013年6月期间住院治疗的68例压疮患者按不同治疗方式随机分为对照组（给予常规治疗）和实验组（纳米银抗菌凝胶＋重组人表皮细胞生长因子）,治疗14 d后比较两组患者治疗效果.结果 实验组患者治疗总有效率达到91.1％,明显高于对照组患者（73.5％）（p＜0.05）；实验组患者创面愈合时间和皮肤愈合时间均明显少于对照组患者（P＜0.05）.结论 纳米银抗菌凝胶联合rhEGF治疗压疮创面效果显著,值得临床推广应用.

Objective To investigate the application of nanometer silver antibacterial gel combined with recombinant human epidermal growth factor （rhEGF） in the treatment of bedsore wound.Methods 68 cases of bedsore wound in our hospital were randomly divided into control group and experimental group from September 2009 to June 2013.Control group received conventional therapy,while experimental group received nanometer silver antibacterial gel ＋ rhEGF.The efficacy of two groups was compared after 14 days＇ treatment.Results The total effective rate of experimental group was 91.1％,significantly higher than 73.5％ of control group （P ＜ 0.05）.The wound healing time and skin healing time of experimental group were shorter than those of control group （P ＜ 0.05）.Conclusion Nanometer silver antibacterial gel combined with recombinant human epidermal growth factor has a significant effect on bedsore wound,which is worthy of clinical application.