高压氧治疗脑出血后抑郁症疗效观察

Analysis of effect of hyperbaric oxygen on depression after cerebral hemorrhage

目的探讨高压氧治疗高血压脑出血后早期抑郁症疗效及其对预后的影响。方法选择该院高血压脑出血早期（按出血开始2～4周）抑郁症患者56例，30例行高压氧治疗，10d为1疗程．连续3疗程。26例给予黛力新治疗。两组患者治疗前用汉密尔顿抑郁量表（HAMD）进行抑郁量化评估，脑出血治疗措施相同，4周后用汉密尔顿抑郁量表（HAMD）进行治疗结果对照分析。结果高压氧治疗组HAMD减分率为76．7％，对照组为61．6％，两组比较差异有统计学意义（P〈O．05）。结论高血压脑出血后早期抑郁症行高压氧治疗，可以改善预后。

[Objective] To discuss the effect of hyperbaric oxygen （HBO） therapy on depression after cerebral hemorrhage. [Methods] All the 56 patients with depression after cerebral hemorrhage divided into two groups （hyperbaric oxygen treatment group 30 and control group 26）. Both were treated with conventional medical treatment, control group 26 treated with Deanxit the HBO group was additionally treated with HBO therapy as soon as the disease condition became stable. Hamilton depression rating scale （HAMD） was measured respectively before therapy and after four weeks therapy. [Results] Barthel index of the HBO group increased significantly after four months＂ therapy when compared with that of the control group, whereas its HAMD decreased obviously （P〈0.01）. [Conclusion] Combined HBO therapy can improve symptom and neurological functional of The patient with expression after cerebral hemorrhage.