我院门诊抗高血压药处方用药分析

Data analysis of outpatient prescriptions of antihypertensive drugs in our hospital

目的了解该院门诊抗高血压药物的应用情况。方法采集2012年上半年每月1、8、15、22日门诊电子处方,以用药频度(DDDs)、日用药金额(DDDDc)、用药金额排序/DDDs排序比值及药物联合应用情况等为指标,分析抗高血药物的应用情况。结果 CCB、ARB和新型复方制剂的使用金额位居前3位,非洛地平、替米沙坦、氨氯地平DDDs最高。联合用药方案多数合理,以二联用药为主。结论抗高血压药物的使用基本符合国内外指南的用药原则,对少数不适宜的联合用药方案有待改进,应根据个体差异选择最佳的药物治疗方案。

Objective To investigate the situation of antihypertensive drugs use in our hospital. Methods Collect the outpatient electronic prescriptions by sampling the prescriptions made on the first, the 8th, the 15th and 22th days every month from January to June 2012. Indicators such as definite daily doses（ DDDs）, daily dose cost （ DDDc）, the order of con- sumption sum to DDDs and joint application of the drug were used to analyze the consumption of antihypertensive drugs. Re- sults Amount in the top three were calcium antagonists （CCBs）, angiotensin lI receptor blockers （ARB）and the new com- pound preparation. Felodipine,telmisartan and amlodipine are the most frequently used drugs. The drugs combination therapies were rational, most of which were combination of two drugs. Colldusion The utilization of antihypertcnsive drugs in our hos- pital is basically in accord with the principle of home and abroad guides. The minority inappropriate drugs combination should be improve. Selecting the best drug treatment programs should be based on individual differences.