血液透析联合血液灌流治疗维持性血液透析患者肾性骨营养不良的临床观察

The Clinical Observation of Treating Renal Osteodystrophy for Maintenance Hemodialysis Patients by Hemodialysis Combining Blood Perfusion

目的分析维持性行血液透析并发生肾性骨营养不良(ROD)患者采用血液透析与血液灌流联合方式治疗的疗效。方法选取2009年2月—2013年2月收治的50例ROD患者,分为治疗组和对照组,分别采用血液透析与血液灌流联合方式以及单用血液透析方式治疗,比较治疗前后两组iPTH、血磷与血钙水平,以及基本疗效。结果两组治疗前较治疗后iPTH和血磷水平降低,血钙水平升高,两组间差异有统计学意义(P<0.05);治疗组总有效率86.7%,对照组为75.0%,两组比较差异有统计学意义(P<0.05)。结论对维持性进行血液透析并发生ROD的患者,采用血液透析与血液灌流联合方式治疗效果明显,值得推广。

Objective To analyze the clinical effect of treating renal osteodystrophy （ROD） for maintenance hemo- dialysis patients by hemodialysis combining blood perfusion. Methods Choosed 50 ROD patients to divide into study group and controlled group. The study group were treated with hemodialysis combining blood perfusion, and controlled group were treateed with hemodialysis only. Compared iPTH, P, Ca of these two groups before and after treatment. Results The total effect rate of study group was 86. 7%, high than 75.0% in controlled group （P 〈 0.05）. Conclusion Treating renal osteodystrophy for maintenance hemodiaIysis patients by hemodialysis combining blood perfusion is effective to extend in clinic.