强直性脊柱炎骶髂关节骨髓水肿SPARCC评分的临床应用研究

The clinical application value of marrow edema SPARCC score of sacroiliac joint in ankylosing spondylitis

目的：探讨强直性脊柱炎（ankylosingspondylitis，AS）骶髂关节骨髓水肿加拿大脊柱骨关节研究协会评分系统（SPARCC）的临床应用价值。方法：收集45例临床确诊的AS患者，依据Bath强直性脊柱炎疾病活动指数（Bathankylosingspondylitisdiseaseactivityindex，BASDAI）评估病情的活动性。患者行骶髂关节MRI及CT扫描，依据sPARCC对As骶髂关节骨髓水肿程度进行评分，分析骨髓水肿SPARCC评分与病情活动性BASDAI评分的相关性。病情进展程度依据AS骶髂关节CT表现分级，分为早期（0-Ⅱ级）和中晚期（Ⅲ-Ⅳ级）2组，比较2组骨髓水肿SPARCC评分差异。结果：骨髓水肿SPARCC评分与病情活动BASDAI评分呈正相关（rs=0．645，P〈0．05），不同病情进展程度2组间骨髓水肿SPARCC评分差异无统计学意义（P〉0．05）。结论：AS骶髂关节骨髓水肿SPARCC评分作为判定病情活动性的依据，可有效、全程监测AS患者病情活动。

Objective： To analyze the clinical application value of marrow edema SPARCC score of sacroiliac joint （SIJs） in an- kylosing spondylitis （AS）. Methods：45 cases with AS confirmed clinically were included. The patients were evaluated by BAS- DAI score and examined by MRI and CT in SIJs. All SIJs were scored according to the spondyloarthritis research consortium of Canada（SPARCC） for bone marrow edema. Correlative analysis was performed between SPARCC score and BASDAI score. According to the CT grade of SIJs of patients with AS,the patients were divided into two groups （the grade of 0-Ⅱ and the grade of Ⅲ-Ⅳ ）. Comparative analysis of SPARCC score was done between two groups. Results：Spearman correlation coef- ficient between SPARCC score and BASDAI score was 0. 645 （P〈0.05）. There was not statistical difference of SPARCC score between the two groups （P〉0.05）. Conclusion： SPARCC score for bone marrow edema can be a base to judge the activity of AS,and can effectively monitor the disease activity of AS patients in the whole process.