瑶族无偿献血者输血传播病毒(TTV)感染分析

Analysis of blood transfusion transmitted virus(TTV) infection in the blood donors of Yao ethnic group

目的研究广东瑶族无偿献血者输血传播病毒(TTV)感染现状。方法采用ELISA法检测血清中抗-TTVIgG,并用PCR法对部分血样进行TTV-DNA检测。结果 376例瑶族无偿献血者检出抗-TTV-IgG阳性176例,阳性率46.81%,男、女阳性率分别为47.94%和45.60%,差异无统计学意义(χ2=0.205,P>0.05)。147例样本检出TTV-DNA 12例,阳性率8.16%,男、女TTV-DNA阳性率分别为9.21%和7.04%,差异无统计学意义(χ2=0.230,P>0.05)。67例抗-TTV-IgG阳性无偿献血者TTV-DNA阳性率5.97%,80例抗-TTV-IgG阴性无偿献血者TTV-DNA阳性率为10.00%,抗-TTV-IgG阳性样本与阴性样本中TTV-DNA阳性率比较差异无统计学意义(χ2=0.790,P>0.05)。结论广东瑶族无偿献血者存在较高TTV既往感染。

Objective To find out the infection status of blood transfusion transmitted virus （rITv） in the blood donors of Yao ethnic group in Guangdong. Methods The anti-TTV-IgG was determined by ELISA. TTV-DNA was detected by Real Time PCR. Results 176 samples among 376 donors were detected positive in anti-TTV-IgG detection, with a positive rate of 46.81%. The positive rates of male and female were 47.94% and 45.60%, respectively. There was no significant difference between male and female （x2=0.205 ,P〉0.05）. 12 were positive for TTV-DNA detection in 147 samples,with a positive rate of 8.16%.The positive rates of male and female wee 9.21% and 7.04%, respectively, showing no significant difference （x2=0.230, P〉0.05）.The TTV-DNA positive rates of positive and negative for the anti -TTV-IgG donors were 5.97% and 10.00%, respectively, showing no difference between male and female （x2=0.790,P〉0.05）. Conclusion A high percentage of blood donors of Yao ethnic group was TTV infected in Guangdong.