2011年深圳市南山区流感暴发疫情分析

Analysis on outbreaks of influenza in Nanshan district, Shenzhen, 2011

目的了解深圳市南山区流感暴发流行的现状和特点,为流感防控提供科学依据。方法采集流感样病例(ILI)咽拭子标本用荧光定量PCR检测,采用狗肾细胞(MDCK)进行病毒分离,微量血凝抑制试验进行鉴定。结果 2011年南山区共报告流感暴发疫情55起,发病507人,平均罹患率为18.76%;流感暴发均发生在托幼机构及中小学,幼儿园、初中、小学三者罹患率分别为20.71%、18.48%、19.93%,差异无统计学意义(P=0.674);共检测ILI咽拭子标本173份,阳性147份,阳性率为84.97%,其中B型流感137份,A型流感10份。结论 2011年南山区流感暴发疫情均发生在托幼机构和学校,今后应加强学校和托幼机构的流感防治。

Objective To study the status and characteristics of influenza in Nanshan district and provide evidences for developing prevention and control measures. Methods Throat swabs were collected from influenza like illness （ILI） patients for influenza virus detecion by PCR and isolation by MDCK cell culture. Hemagglutination inhibition test was conducted to identify the types or subtypes of isolated strains. Results There were 55 influenza outbreaks and 507 cases in Nanshan district, 2011. The average attack rate was 18.76%.The influenza outbreaks mainly took place in the childcare facilities and primary and secondary schools. The attack rate in kindergarten primary secondary school was 20.71%, 18.48%, 19.93% ,showing no statistically significant difference （P〉0.05）. 173 specimens from the outbreaks of influenza were collected, of which 147 specimens （84.97%） were positive. Influenza B virus （137/147） was the main strain in outbreaks in 2011. Conclusions All the outbreaks of influenza took place in school and nursery. It is necessary to strengthen the disease surveillance and take timely prevention and control measures in school and nursery.