山东省沂源县西部地区恙虫病东方体、地方性斑疹伤寒和斑点热立克次体血清流行病学的初步研究

Preliminary research of seroepidemiology on seroprevalence of Orientia tsutsugamushi,Rickettsia typhi and Spotted fever rickettsia in rural populations in the west of Yiyuan,Shandong Province of China

目的了解近年山东省沂源县西部地区农村人口恙虫病东方体、地方性斑疹伤寒立克次体和斑点热立克次体的感染情况,为自然疫源性疾病的预防和控制提供依据。方法 2011年从山东省沂源县西部乡镇的农村人口中随机收集192份血清,采用间接免疫荧光法检测血清中恙虫病东方体、地方性斑疹伤寒立克次体和斑点热立克次体抗体。结果恙虫病东方体、地方性斑疹伤寒立克次体和斑点热立克次体抗体血清阳性率分别为56.77%(109/192)、79.69%(153/192)和69.79%(134/192)。结论山东省沂源县西部农村人口中恙虫病东方体、地方性斑疹伤寒立克次体和斑点热立克次体的感染率较高。

Objective To study the rickettsial disease infection situation in rural populations in the west of Yiyuan and pro- vide scientific basis to control and prevent natural focal diseases. Methods We collected 192 sera from farmers in the west of Yiyuan County, Shandong Province and tested them by indirect-immunofluorescence assay （IFA） for antibodies of Orientia tsutsugamushi, Rickettsia typhi and Spotted fever rickettsia. Results 56.77% （ 109/192）, 79.69% （ 153/ 192） and 69.79% （134/192） sera were positive for antibodies of Orientia tsutsugamushi, Rickettsia typhi and Spotted fever rickettsia, respectively. Conclusion The results indicate high prevalences of these rickettsial diseases in this area.