腹膜透析患者长期生存及影响预后的相关因素分析

Analysis of long-term survival and related factors in peritoneal dialysis patients

目的分析长期腹膜透析(PD)患者的临床数据,探讨其远期预后及影响的相关因素。方法所有患者均应用规范透析剂量,置管后3～4周按照PET法留置标本,应用PD Adequest软件计算,对腹膜转运类型进行确定,同时制定透析方案。结果观察组的血白蛋白、残余肾Kt/V、残余肾Ccr、GFR明显高于对照组,脉压差明显低于对照组(P<0.05)。随访1年、2年、3年观察组总GFR中位数、血糖升高及腹膜炎发生率与对照组比较均明显改善(P<0.05)。结论 PD患者生存率较高,长期PD患者透析后肾功能降低速度缓慢,且不易发生腹膜炎。

[Objective ] To investigate the clinical features in long-term peritoneal dialysis patients and related factors effected to long-term prognosis. [Methods] All patients using standard dialysis dose for 3-4 weeks after catheter indwelling samples according to the method of PET, the peritoneal transport type was calculated and determined using the PD Adequest software, while developing dialysis programs. [ Results ] Serum albumin, residual renal Kt/V, residual renal Ccr, GFR in study group were significantly higher than control group. Pulse pressure was significantly lower than in the control group （P 〈0.05）. Follow-up of 1 years, 2 years, 3 years, the median of GFR, blood sugar and the peritonitis rate in study group were obviously improved （P 〈0.05）. [ Conclusions ] Peritoneal dialysis patients have higher survival rate, and kidney function is reduced slowly after long-term peritoneal dialysis, less prone to peritonitis.