慢性乙肝患者生命质量及影响因素分析

Quality of life and its influencing factors among chronic hepatitis B patients

目的评价慢性乙肝患者生命质量,并探讨其影响因素。方法采取随机整群抽样方法,使用健康调查简易量表SF-36对291例患者进行调查,运用ordinal logistic回归等方法对有效调查信息进行分析。结果慢性乙型肝炎患者总体健康(GH)、生理功能(PF)、生理职能(RP)、情感职能(RE)、社会功能(SF)、躯体疼痛(BP)、活力(VT)和精神健康(MH)得分分别为(50.41±19.70)、(69.74±35.06)、(32.41±44.81)、(64.25±46.31)、(78.71±24.37)、(73.03±23.50)、(55.60±17.90)、(64.65±17.20)分,与中国常模比较,差异均有统计学意义(均P<0.001);Ordinal logistic回归分析结果显示,未患其他慢性病、门诊患者、年龄小以及家庭人均年收入高的乙肝患者生命质量越高(均P<0.05)。结论乙肝患者生命质量低于一般人群且受到多种因素影响。

Objective To evaluate the quality of life（QOL） in patients with chronic hepatitis B and to explore its influencing factors.Methods Cluster random sampling was taken and the Medical Outcomes Study 36-Iterm Short Form Health Survey（SF-36） was used among 342 chronic hepatitis B patients.The data collected were analyzed by using ordinal logistic regression analysis.Results Compared with the domestic norm,the scores of general health（50.41±19.70）,physical functioning（69.74±35.06）,role-physical（32.41±44.81）,role-emotional（64.25±46.31）,social functioning（78.71±24.37）,bodily pain（73.03±23.50）,vitality（55.60±17.90）,and mental health（64.65±17.20）were lower（P〈0.001 for all） among the patients.Results of ordinal logistic regression analysis showed that age,chronic diseases,and hospitalization had negative influence on QOL,but higher per capita income had positive influence（P〈0.05）.Conclusion The patients with chronic hepatitis B had poorer QOL than general population and the QOL of the patients was influenced by a number of factors.