广西壮族自治区农村居民抑郁症流行病学调查

Epidemiological survey on depression disorders among rural residents in Guangxi Zhuang Autonomous Region

目的 了解广西壮族自治区农村居民抑郁症的患病水平和分布特征。方法 采用多阶段分层整群随机抽样方法抽取广西壮族自治区10个县≥15岁常住居民共11 191人,采用复合性国际诊断问卷3.0版（CIDI 3.0）和自编调查表进行面访调查,并采用国际疾病及相关健康问题分类第10版（ICD-10）进行诊断。结果 广西壮族自治区农村居民抑郁症时点患病率和终生患病率分别为3.66‰和5.27‰;男性和女性居民的时点患病率分别为2.40‰和5.05‰,不同性别农村居民时点患病率间差异有统计学意义（χ2=5.355,P=0.021）;15-、25-、35-、45-、55-、65-、≥75岁居民时点患病率分别为1.74‰、1.33‰、3.40‰、4.88‰、8.87‰、1.25‰、6.74‰,终生患病率分别为4.63‰、2.65‰、4.91‰、4.88‰、12.29‰、3.75‰、4.49‰,不同年龄农村居民时点患病率和终生患病率间差异均有统计学意义（P〈0.01）;未婚、在婚、离婚/丧偶居民的时点患病率分别为1.64‰、3.27‰、18.44‰,终生患病率分别为4.37‰、4.51‰、22.54‰,不同婚姻状况农村居民时点患病率和终生患病率间差异均有统计学意义（P=0.000）。结论 女性、年龄55-64岁、离婚/丧偶的农村居民是抑郁症预防的重点人群。

Objective To investigate the prevalence and distribution of depression disorders among people aged more than 15 years in rural areas of Guangxi Zhuang Autonomous Region.Methods From July to December 2007,13 910 subjects aged more than 15 years were randomly selected with stratified multi-stage cluster sampling.All subjects were investigated with a face-to-face interview.The Composite International Diagnostic Interview 3.0（CIDI 3.0） was used as the screening tool and the diagnoses were made based on International Classification of Disease -10th Edition.Results Totally 11 191 subjects completed the screening and the completion rate was 80.45%.The overall point prevalence was 3.66‰ and the overally lifetime prevalence was 5.27‰.The overall lifetime prevalence of depression disorders was higher in the female（6.54‰） than in the male（4.11‰）,but the difference was not significant（P〉0.05）.There were significant differences in the lifetime prevalence among the people of different age and marriage status（P〈0.05）,with higher prevalences of depression disorders in the people aged 55-64 years and the divorced.There were no significant differences（P〉0.05） in the lifetime prevalence among the people with different education level and between Zhuang and Han ethnicity.Conclusion The prevalence of depression disorders is high among rural residents in Guangxi and strategy should be made to prevent and control the disease.