乙肝肝硬化患者脾栓塞术后抗病毒治疗的重要性

Hepatitis B Patients with Cirrhosis of the Liver and Spleen Embolization Postoperative Antiviral Treatment Curative Effect Analysis

目的:观察乙肝肝硬化并发脾功能亢进患者行部分脾栓塞术后抗病毒治疗的疗效。方法:对160例乙肝肝硬化并发脾亢患者进行观察,按照患者部分脾栓塞术后是否进行抗病毒治疗将其分为两组,A组80例未行抗病毒治疗,B组80例行抗病毒治疗。对上述患者进行6个月的观察,包括病毒载量、肝功能检查及上消化道出血情况。结果:A组治疗第6个月的各项肝功能监测数据明显高于B组,差异具有统计学意义(P<0.05);A组治疗3个月后乙肝病毒载量及发生再发性消化道出血的患者均明显高于B组,差异具有统计学意义(P<0.05)。结论:部分脾栓塞术后乙肝病毒载量均有升高,且肝功能无明显改善,而加强术后抗病毒治疗,可以改善肝功能,提高患者生活质量,延长生存期。

Objective： To observe hepatitis b cirrhosis patients complicated with the splenic function after partial splenic embolization postoperative antiviral of treatment the curative effect. Method： 160 cases with hepatitis B liver cirrhosis complicated with hypersplenism patients according to whether on postoperative antiviral treatment was divided into two groups, 80 cases of group A was no antiviral treatment group, 80 cases of group B antiviral treatment group. Observed the patients＇ viral load, liver function and upper gastrointestinal bleeding for six months. Result： A group treatment 6 months was significantly higher than group B and differences in the had statistically significant （ P〈0.05 ） ; Postoperative 3 months after the group A patients with recurrent gastrointestinal bleeding, and hepatitis B viral load were significantly higher than that of group B, differences had statistically significant （ P〈0.05 ） . Conclusion： After partial splenic embolization of hepatitis b viral load are higher, and no obvious improve liver function, and strengthen the postoperative antiviral treatment, can improve the liver function, and improve patients quality of life and prolong the survival period.