利多卡因与胺碘酮在颅脑损伤并发急性室性心律失常中的疗效对比

Comparison of the efficacy of lidocaine and amiodarone in the treatment of traumatic brain injury complicated by acute ventricular arrhythmia

目的对比利多卡因与胺碘酮在发作急性室性心律失常的颅脑损伤患者中的疗效。方法 236例颅脑损伤并发急性室性心律失常患者随机分成利多卡因组和胺碘酮组,分别给予利多卡因和胺碘酮行抗心律失常治疗,对比2组疗效。结果利多卡因组总有效率69.49%(82/118),胺碘酮组总有效率84.75%(100/118),胺碘酮组总有效率显著高于利多卡因组(P<0.05)。结论在颅脑损伤合并急性室性心律失常的治疗中,胺碘酮效果优于利多卡因,可作为首选。

Objective To compare the clinical efficacy of lidocaine and amiodarone in the treatment of traumatic brain inju- ry complicated by acute ventricular arrhythmia. Methods Totally 236 cases of patients were randomly divided into two groups. Lidocaine group was treated by lidocaine, and amiodarone group was given amiodarone, the clinical efficacy was observed and compared. Results After treatment, the total effective rate of lidocaine group was 69.49 % （ 82/118）, the total effective rate of amiodarone group was 84.75 % （100/118）. The total effective rate of amiodarone group was significantly higher than that of lidocaine group（P〈0.05）. Conclusion In treatment of patients with traumatic brain injury complicated by acute ventricular arrhythmia, amiodarone is better than lidocaine, and can be used as the first choice.