期刊文献+

调节性T细胞的研究进展 被引量:1

下载PDF
导出
摘要 调节性T细胞具有免疫低反应性和免疫调节功能两大特征。它们在自身免疫性疾病的治疗、肿瘤的治疗以及移植耐受的诱导等方面具有广泛的应用价值。本文对调节性T细胞的产生、类型以及在自身免疫性疾病,移植免疫耐受和肿瘤免疫方面的研究进行综述。
作者 杨永红 袁军
出处 《贵州医药》 CAS 2013年第10期941-944,共4页 Guizhou Medical Journal
  • 相关文献

参考文献21

  • 1Sakaguchi S, Sakaguchi N, Asano M, et al. Immuno- logic self-tolerance maintained by activated T cells ex- pressing IL-2 receptor alpha-chains (CD25). Break- down of a single meehanismof self-tolerance causes va- rious autoimmune diseases[J]. J Immunol, 1995,155 : 1151-1164.
  • 2Rafal P,Piofr K,Lesze K I. Peptide specificity of thy- mic selection for CD4^+ ,CD25^+T cell [J]. J Immunol, 2002,168(2) :613-620.
  • 3Modiglian Y, Coutinho P, Pereira N, et al. Establish- ment of tissue-specific tolerance is driven by regulatory T cellsselected by thymic epithelium [J]. Eur J Immunol, 1996,26 (8) : 1807-1815.
  • 4Seddon B, Mason D. Peripheral autoantigen induces regulatory T eells that prevent autoimmunity [J]. J Exp Med,1999,189(5) :877.
  • 5Jordan MS, Boesteanu A, Reed AJ, et al. Thymic selec- tion of CD4+ ,CD25+ regulatory T cells induced by an agonist self-peptide[J]. Nature Immunol, 2001,2 (4) : 301-306.
  • 6Ethan MS. Regulatory T cells in Autoimmunity[J]. Annu Rew Immunol, 2000,18: 423-449.
  • 7Malek TR, Yu A, Vincek V, et al. CD4 regulatory T cells prevent lethal au-toimmunity in IL-2Rbeta-defi- cient mice. Implications for the nonredundant function of IL-2[J] . Immunity, 2002,17 (2): 167-178.
  • 8Boden E, Tang Q, Bourordan H, et al. The role of CD28 and CILA4 in the function and homeostasis of CD4+ ,CD25+ regulatory T cells[J]. Novartis Found Symp, 2003,252 : 55-63.
  • 9HO I, Glimcher LH. Critical roles for transcription factor GATA-3 in thymocyte development Cell[J]. Immunity, 2003,19 : 863-875.
  • 10Jeffrey AB,Abul KA. Natural versus adaptive regula- tory T eelts[J] . Nature Reviews Immunology,2003,3 (3) :253-257.

同被引文献5

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部