原发性肺黏液腺癌的临床特点和外科治疗

Clinical Features and Surgical Treatment of Primary Pulmonary Mucinous Adenocarcinoma

目的总结原发性肺黏液腺癌(PPMA)的临床特点及外科治疗方式。方法对我院2006年1月—2012年1月收治的12例PPMA患者的临床资料进行回顾性分析。结果 12例PPMA患者,手术治疗11例,其中6例电视辅助胸腔镜外科手术(VATS)、5例开胸手术,均经病理组织活检确诊,病理分期:Ⅰb期4例,Ⅱa期2例,Ⅱb期2例,Ⅲa期3例,Ⅳ期1例。12例患者中11例为周围型占位,1例疑为中央型占位。行VATS患者术后引流量、术中出血量低于开胸手术患者(P<0.05)。结论 PPMA临床和影像学表现无特异性,通过病理组织活检确诊;其首选的治疗方式是手术治疗,其中VATS更具优势;PPMA有一定的异质性,应采用综合治疗方案,以促进患者康复。

Objective To Summarize the clinical characteristics and surgical treatment of primary pulmonary mucinous adenoearcinoma （PPMA）. Methods The clinical data of 12 PPMA patients in our hospital were retrospectively analyzed from January 2006 to January 2012. Results In the 12 PPMA patients, 11 cases were given surgical treatment, including 6 cases of video -assisted thoracoscopie surgery （VATS） , 5 cases of thoracotomy, they were pathologically diagnosed. Pathological stage： stage I b of 4 eases, stage 1I a of 2 cases, stage 11 b of 2 cases, stage m of 3 eases, stage IV of 1 case. Including 11 cases of peripheral mass, 1 case of suspected central type. The postoperative drainage, blood loss of VATS patients were lower than those of thoracotomy patients （ P 〈 O. 05 ）. Conclusion PPMA clinical and imaging findings are nonspecific, diagnosis through path- ologieal biopsy; Its preferred treatment is surgery, in which VATS has better advantage; PPMA has some heterogeneity, com- prehensive treatment program should be used to promote the rehabilitation of patients.