高龄非糖尿病患者低血糖症前期相关因素分析

The analysis of relevant issues associated with early stage hypoglycemia in elderly non diabetes mellitus patients

目的探讨高龄非糖尿病住院病人低血糖症前期的发生及相关因素。方法收集2011年3月至2013年3月住院老年非糖尿病人无症状低血糖症前期者20例,空腹血糖正常者20例作为对照。了解所有这些患者的肝、肾、甲状腺功能,是否合并肿瘤、摄食情况及空腹C肽、皮质醇水平等。结果 Logistic多原回归分析提示前白蛋白、C肽为影响高龄非糖尿病住院病人空腹血糖的独立危险因素。结论空腹C肽、前白蛋白水平、进食方式与高龄非糖尿病患者空腹血糖偏低的发生有关,肝、肾、甲状腺功能等对其影响不大。

Objective To investigate relevant issues associated with early stage hypoglycemia in elderly non diabetes mellitus patients. Methods The relevant clinical data of 40 elderly patients were collected between March 2011 and March 2013. Twenty patients were diagnosed as early stage of hypoglycemia without diabetes mellitus. Twenty patients were control subjects with normal fasting blood glucose. The relevant con ditions were analyzed, including liver function, renal function, thyroid function, whether or not associated with tumor, ingestion condition, C peptide and cortisol level. Results The SPSS 18.0 was used as statistics analysis software. The multiple logistic regression was used to analyze the influence of prealbumin, C peptide on fasting blood glucose. The statistical analysis showed the prealbumin and C peptide were the inde pendent risk factors influencing the fasting blood glucose of elderly non diabetes mellitus patients. Conclusion The levels of fasting C peptide and prealbumin and feeding style, but not the functions of liver, renal and thyroid relate to the low fasting blood glucose in elderly non diabetes mellitus patients.