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细胞移植治疗的临床应用及发展——细胞移植治疗连载之三

The Clinic Application and Development of Cell Transplantation Therapy
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摘要 细胞移植治疗在临床上的应用在几百年前就有尝试,但规模化的临床应用还是近年来的事。细胞移植治疗的临床应用领域包括血液系统疾病、心血管系统疾病、消化系统疾病、神经系统疾病、免疫系统疾病、呼吸系统疾病、泌尿系统疾病、骨骼系统疾病以及抗衰老、角膜损伤、视网膜损伤、皮肤损伤、烧伤等。加拿大、韩国、美国等国已有干细胞药物被批准临床应用。2013年,中国干细胞移植治疗管理也实现了从"技术"到"制剂(药物)"的转变。细胞移植治疗将具有良好的发展前景。 Cell transplantation therapy was used in clinic since hundreds of years ago, however until recent years it began to large-scale apply in clinic. The application area of cell transplantation therapy include diseases in hematological system, cardiovascular system, digestive system, nervous system, immune system, respiratory system, urinary system, and skeletal system, also include anti-aging, corneal injury, retina injury, skin injury, and empyrosis etc. Stem cell drugs have already been approved to apply in clinic in Canada, Korea, and America. In 2013, the administration of cell transplantation therapy in China begin to transform from technique to agent or drug. Cell transplantation therapy will have good development prospect.
作者 王佃亮
出处 《中国生物工程杂志》 CAS CSCD 北大核心 2013年第10期138-145,共8页 China Biotechnology
关键词 细胞移植 细胞治疗 临床应用 干细胞制剂 干细胞药物 Cell transplantation Cell therapy Clinic application Stem cell agent Stem cell drug
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  • 1Snow J L, Kawut S M. Surrogate end points in pulmonary arterial hypertension: assessing the response to therapy. Clin Chest Med, 2007,28:75-89.
  • 2Tse H F, Kwong Y L, Chan J K, et al. Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation: Lancet, 2003,361:47-49.
  • 3Wang Y, Yang D, Song L, et al. Mifepristone-inducible caspase- 1 expression in mouse embryonic stem cells eliminates tumor formation but spares differentiated cells in vitro and in vivo. Stem Cells, 2012, 30(2) :169-179.
  • 4Weiss D J, Kolls J K, Ortiz L A, et al. Stem cells and cell therapies in lung biology and lung diseases. Proc Am Thorac Soc, 2008,5 ( 5 ) :637-667.
  • 5Yoon C H, Hur J, Park K W, et al. Synergistic neovascularization by mixed transplantalion of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinases. Circulation, 2005, 112: 1618- 1627.
  • 6Wilkinson N, Scott-Conner C E. Surgical therapy for colorectal adenocarcinoma. Gastroenterol. Clin. North Am, 2008,37 ( 1 ) : 253 -267.
  • 7Young W F, McGloin J, Zittleman L, et al. Predictors of colorectal screening in rural Colorado: testing to prevent colon cancer in the high plains research network. J Rural Health, 2007,23(3 ) :238-245.
  • 8Thornton A J, Alsberg E, Albertelli M, et al. Shape-defining scaffolds for minimally invasive tissue engineering. Transplantation, 2004,77 : 1798-1803.
  • 9Zhou P, Liang P, Dong B, et al. Phase I clinical study of combination therapy with microwave ablation and cellular immunotherapy in hepatocellular carcinoma. Cancer Biol Ther,2011,11 (5) :450-456.
  • 10Thenappan A, Li Y, Shetty K, et al. New therapeutics targeting colon cancer stem cells. Curr Coloreetal Cancer Rep, 2009,5 (4) :209.

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