四逆汤加味治疗82例功能性便秘的临床观察

Exploration on Effect of Sini Decoction on 82 Functional Constipation Patients

目的:探讨四逆汤加味治疗功能性便秘的疗效。方法:将82例功能性便秘患者随机分为治疗组和对照组,对照组采用乳果糖治疗,治疗组采用四逆汤加味治疗,2组均以1个月为1个疗程。评价临床症状积分及生活质量改善情况。结果:治疗组总有效率81.4%,对照组总有效率56.4%,经统计学处理差异有统计学意义(P<0.05),PAC-QOL量表积分治疗后较治疗前降低有统计学意义。结论:四逆汤加味能有效改善功能性便秘患者的症状及生活质量。

Objective： To explore the effect of Sini decoction on functional constipation patients.Methods： Eighty-two cases of functional constipation patients were randomly divided into treatment group and control group.The control group received lactulose therapy,while the treatment group were given Sini decoction medicine therapy.Both the control group and treatment group received the corresponding treatment for one month and the quality of life and improvement of clinical symptoms were assessed.Results： The total effective rate in treatment group and control group were respectively 81.4% and 56.4%.Significant difference was observed between the two groups（P 0.05）,and PAC-QOL scale scores after treatment than before treatment decreased with statistical significance.Conclusion： Sini decoction therapy of traditional Chinese medicine is effective in relieving clinical symptoms and enhancing life quality of functional constipation patients.