氧气驱动雾化吸入防治鼻咽癌放疗患者放射性口腔黏膜炎的效果

Effect of oxygen-driven aerosol inhalation on nasopharyngeal carcinomapatients＇ radiogenic stomatitis

目的 探讨氧气驱动雾化吸入对鼻咽癌患者放疗致口腔黏膜炎的临床防治效果.方法 将接受单纯放疗的100例鼻咽癌患者随机分为两组,对照组（n=50）采用超声雾化吸人,观察组（n=50）采用氧气驱动雾化吸入,观察两种方法对放射性口腔黏膜炎的防治效果.结果 放疗4～6周时对照组Ⅲ～Ⅳ级口腔黏膜反应程度分别为26％,30％,16％；观察组分别为14％,12％,4％；两组患者放射性口腔炎反应程度比较差异有统计学意义（u值分别为2.0646,2.8145,2.361;P ＜0.05）.结论 鼻咽癌放疗患者采用氧气驱动雾化吸入能明显减轻口腔黏膜炎的反应程度,减轻患者痛苦,提高患者生存质量.

Objective To study the effects of oxygen-driven aerosol inhalation on nasopharyngeal carcinoma patients＇ radiogenic stomatitis.Methods Totals of 100 patients with nasopharyngeal carcinoma were divided into the test group （n =50） and control group （n =50） randomly.The control group was treated by the conventional way that using ultrasonic nebulizer,while the test group was treated by using the method of oxygendriven aerosol inhalation.Results At the end of the fourth week,fifth week,and the sixth week after the intervention,patients of the test group was obviously different than the control group in reaction of mouth mucous membrane [14％ vs 26％,12％ vs 30％,4％ vs 16％ ;u =2.0646,2.8145,2.361,respectively;P ＜0.05].Conclusions Oxygen-driven aerosol inhalation on nasopharyngeal carcinoma patients＇ radiogenic stomatitis can prevent stomatitis,relieve the patients＇ pain and improve their life quality.