摘要
近年来柯萨奇病毒A组16型(coxsackievirus A16,CVA16)和肠道病毒71型(enterovirus 71,EV71)在我国引起了手足口病(HFMD)的暴发和流行.CVA16感染的生物学基础研究有助于提高HFMD的防治水平,为HFMD疫苗的研发提供重要依据,此文就CVA16的生物学特性及其与宿主细胞相互作用的研究进展作一综述.
The outbreaks of hand,foot and mouth disease (HFMD)caused by coxsackievirus A16 (CVA16) and enterovirus 71 (EV71) occurred in China in recent years.The fundamental research on biological characteristics of CVA16 infection plays a vital role in improving HFMD control and prevention,and developing effective HFMD vaccines.This review summarizes the research progress in biological characteristics of CVA16 and interaction between the virus and host cells.
出处
《国际生物制品学杂志》
CAS
2013年第5期257-261,共5页
International Journal of Biologicals
基金
国家重点基础研究发展计划(2011CB504903)
国家自然科学基金(81171573)
关键词
柯萨奇病毒
肠道病毒属
手足口病
Coxsackievirus
Enterovirus
Hand,foot and mouth disease