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老年冠心病患者胱抑素C、β_2微球蛋白水平及临床意义 被引量:19

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摘要 目的观察老年冠心病(CHD)患者胱抑素C(Cys-C)、β2微球蛋白(β2-MG)水平及其与冠状动脉病变,左心功能的关系。方法入选年龄≥65岁的住院CHD患者150例(CHD组),同期入选<65岁CHD患者150例为对照组及≥65岁冠状动脉造影阴性患者100例为非冠心病组(非CHD组),比较三组患者一般资料及Cys C、β2-MG水平,评价老年CHD患者Cys C、β2-MG水平与CHD类型、冠状动脉病变、左心功能关。结果与同年龄段非CHD患者比较,老年CHD患者Cys C水平较低(P>0.05);同<65岁CHD患者比较老年患者Cys C和β2-MG水平明显增高(P<0.05);老年CHD三支病变者和重度病变者Cys C水平明显低于单支病变和轻度病变者(P<0.05)。结论老年人Cys C,β2-MG水平高于非老年者;老年CHD患者随着冠状动脉病变数目、病变严重程度的增加,Cys C水平逐渐降低。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2013年第21期5262-5264,共3页 Chinese Journal of Gerontology
基金 辽宁省科学技术计划项目(No.2010020241-418) 沈阳市科学技术计划项目(No.F11-262-9-18)
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二级参考文献17

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