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离子通道在肝细胞癌发生发展中的作用 被引量：1

Role of ion channels in the development and progression of hepatocellular carcinoma
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摘要 离子通道是一类微孔细胞膜蛋白质,是维持机体生命活动的重要组分.其本身表达和活性的异常改变与肿瘤细胞的增殖和凋亡密切相关.本文系统阐述4种离子通道与肝细胞癌的关系及在其发生发展中的作用,提示离子通道有可能成为肝细胞癌的新的药物治疗靶点. Ion channels are pore-forming membrane proteins which play regulatory roles in a variety of biological processes. Their abnormality in expression or activity has a close relationship with the proliferation and apoptosis of cancer cells. This article will describe the role of four ion channels in the development and progression of hepatocellular carcinoma. Our review suggests that ion channels might be a new therapeutic target for hepatocellular carcinoma.
作者 刘雪梅 庹必光
机构地区 遵义医学院附属医院消化内科 贵州省消化疾病研究所
出处 《世界华人消化杂志》 CAS 北大核心 2013年第29期3041-3046,共6页 World Chinese Journal of Digestology
关键词 离子通道 肝细胞癌 发生 发展 Ion channels Hepatocellular carcinoma Development Progression
分类号 R735.7 [医药卫生—肿瘤]
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参考文献50

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同被引文献15

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世界华人消化杂志
2013年 第29期

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