颈静脉球瘤的三维立体适形放疗3例报告

3 cases report of 3 dimensional conformal radiation therapy for glomus jugulare tumors

目的:探讨三维立体适形放疗治疗颈静脉球瘤的临床疗效。方法:回顾性分析3例颈静脉球瘤的临床资料,3例均采用三维立体适形放疗,肿瘤体积约2-8cm3,肿瘤DT达45-55Gy/9-11f/3-3.5w,随访1-8年。结果:1例头痛、头晕、耳鸣、耳聋等症状完全缓解,复查颅脑增强MRI显示病灶明显缩小;1例耳鸣、头痛、头晕、手足震颤、出汗均消失,继发性高血压自愈,复查颅脑增强MRI显示病灶缩小;1例耳鸣减轻,颅脑CT显示肿瘤稳定。随访后病情均稳定,无复发或转移。结论:三维立体适形放疗能较好的控制肿瘤生长,无明显不良反应,可作为不适合手术、拒绝手术的颈静脉球瘤病人首选的治疗方法,同时也是术后肿瘤残留或复发的重要治疗手段。

Objective：To assess the clinical efficacy of 3 dimensional conformal radiation therapy for glomus jugulare tumors.Methods：The clinical data of 3 patients with glomus jugulare tumor were analyzed retrospectively.All cases were treated by 3D-CRT （3 dimensional conformal radiation therapy）.The volume range of tumors was 2-8cm3,tumors DT 45-55Gy/9-11f/3-3.5w,patients were followed up for 1-8 years after therapy.Results：No patient suffered a new cranial nerve deficit after 3D-CRT.The clinical symptoms virtually disappeared in 2 cases,clinically improved in 1.The follow-up period was 1-8 years.The tumor size decreased in 2 cases,unchanged in 1 case.Conclusion：3D-CRT can effectively control tumor growth with mild side-effects and be used to treat small glomus jugulare tumors or for patients who are not suitable for craniotomy.It is also an important method for treating residual tumors.