摘要
目的:分析动脉插管灌注化疗联合手术在子宫颈癌治疗中的临床应用价值。方法:我院收治的符合观察标准的子宫颈癌患者60例,随机分成A组和B组,A组患者给予动脉插管灌注化疗+手术治疗,B组患者给予单纯手术治疗。比较两组患者化疗疗效、手术情况以及术后3a、5a生存率。结果:B组患者完全有效(Complete Response,CR)率为0、部分缓解(partial response,PR)率10.00%,A组患者CR率20.00%,PR率为66.67%%,两组比较P<0.01,B组患者术中出血(422.71±29.42)mL,手术时间(3.97±0.84)h,A组患者术中出血(351.64±25.14)mL,手术时间(3.14±0.51)h,两组比较,P<0.01,B组患者3a生存率达66.67%、5a生存率达46.67%,A组患者3a生存率达90.00%、5a生存率达76.67%,两组比较P<0.05,差异具有统计学意义。结论:动脉插管灌注化疗联合手术治疗子宫颈癌疗效好、手术时间短、术中出血少、术后生存率高,值得在临床推广。
Objective:Analyse the clinical value of arterial infusion chemotherapy and surgery in the treatment of cervical cancer. Methods:Consistent with the observed standard hospital patients with cervical cancer, 60 patients were randomly divided into Group A and Group B, Group A of patients given arterial intubation chemotherapy and surgical treatment, Group B patients with surgical treat- ment. The two groups were compared the chemotherapy, surgery situation, and after 3 years, 5 - year survival rate. Results: B group of patients with CR rate of 0, PR rate of 10% and CR rate of the A group of patients is 20.00%, the PR rate was 66.67%, compared between the two groups, P 〈0.01, B group patienta with blood loss (422.71 ±29.42) ml, operative time (3.97 ±0.84) h, A group of patients with blood loss (351.64± 25.14) ml, surgery time (3.14 ± 0.51 ) h, compared between the two groups, P 〈0. 01, Patients in group B 3 - year survival rate was 66.67%, 5 - year survival rate was 46.67%, A group patients with 3 - year survival rate was 90.00%, 5 - year survival rate was 76.67% compared between the two groups, P 〈 0.05, a statistically significant diffe.r- ence. Concluslon:Arterial infusion chemotherapy and surgical treatment of cervical cancer is effective, shorter operative time, less blood loss, postoperative survival rate, it is' worth in clinical practice.
出处
《牡丹江医学院学报》
2013年第5期24-26,共3页
Journal of Mudanjiang Medical University
关键词
动脉插管灌注化疗
手术
子宫颈癌
临床
Arterial infusion chemotherapy
Surgery
Cervical cancer
Clinical