口腔颌面部多间隙感染老年患者与中青年患者的临床比较

Comparison of Multi-space Infections of the Head and Neck in Adults and the Aged Patients:A Retrospective Study of 242 Cases

目的:通过与中青年患者的比较,分析口腔颌面部多间隙感染老年患者的临床特征。方法:对上海第九人民医院口腔颌面外科收治的242例诊断为口腔颌面部多间隙感染的病例进行回顾性分析。所有病例根据年龄分为老年组和中青年组。研究内容包括一般资料、临床指标(全身系统性疾病、病因、症状发作到入院治疗的时间、受累间隙的数量和分布)、实验室检查(细菌学、入院时血糖水平、入院时白细胞总数和中性粒细胞百分比)和治疗结果(切口数量、住院天数和并发症)。采用SAS 8.0软件包对数据进行t检验、Fisher’s确切概率和χ2检验分析。结果:与中青年患者相比,老年患者患有更多的系统性疾病(P=0.0002),住院时程更长(P=0.02),全身各种并发症情况更多见(P=0.04)。结论:通过与中青年患者比较,揭示了口腔颌面部多间隙感染中的老年患者的临床特征,为临床上治疗老年口腔颌面部多间隙感染提供了重要的参考依据。

Objective： This study aimed to retrospective analyze the difference between the aged patients （≥60 years） and adults （〈60 years） with multi-space infections of the head and neck. Methods： 242 patients received treatment for severe multi-space infections of the head and neck region. Demographics, clinical parameters （the coexisting conditions, the etiology, the length between first symptomatic onset and admission, the number of spaces affected, and the distribution of involved spaces）, laboratory values （bacteriology, admission blood glucose level, admission white blood cell count, and percent of neutrophil on admission） and treatment parameters （the number of incisions, complications and length of hospital stay） were collected and analyzed for their clinical significance. Statistical analyses between groups were performed using the Student t test, Fisher＇s exact test, and chi-square. Results： Compared with the adults, the elders had more system diseases （P=0.0002）, bad longer hospital stays （P=0.02）, and developed more complications （P=0.04）. Conclusion： This study demonstrated the differences existed in clinical features between the adult and the aged patients with multi- space infections of the head and neck.