2009年-2011年红河州流感监测结果分析

Analysis of influenza monitoring results in Honghe prefecture from 2009 to 2011

目的了解2009年-2011年红河州流感的流行特征，为流感防控提供依据。方法哨点医院每周采集5份～15份流感样病例咽拭子标本，用MDCK细胞分离流感病毒，用红细胞凝集法（HA）和红细胞凝集抑制法（HI）鉴定病毒。县（市）CDC送检标本用Real—timePCR方法进行病毒鉴定。结果2009年-2011年共采集标本1727份分离毒株347份，分离率20．1％。其中A型季节性H1N1亚型10株，占2．9％；H3N2亚型88株，占25．4％，甲型H1N1亚型181株，占52．2％；B型Victoria系57株，占16．4％；B型Yamagada系11株，占3．2％。结论2009年以甲型H1N1型流感病毒为主要优势流行株；2010年以H3N2型流感为主要优势流行株；2011年以B型流感病毒流行为主。

Objective To understand the epidemic characteristics of influenza in Honghe prefecture, and provide basis for pre- vention and control of influenza. Methods Five to fifteen throat swabs specimens were collected from influenza - like illness cases every week in sentinel hospital. The influenza virus were isolated by MDCK cell, and identified by hemagglutination test （HA） and hemagglutination inhibition test（HI）. The samples from county CDC were identified by real -time PCR. Results A total of 1727 throat swabs were collected from 2009 to 2011, and 347 strains of influenza virus were isolated（20. 1% ）, among them, 10 strains were A（ H1N1 ） virus（2.9% ）, 88 strains were H3N2 virus （25.4%）, 181 strains were pandemic influenza A （ H1 N1 ） （52.2%）, 57 strains were B/Victoria lineage virus （ 16.4% ）, 11 strains were B/Yamagata lineage virus （ 3.2% ）. Conclusion The predominant strain was influenza A （ H1 N1 ） in 2009, influenza H3N2 in 2010 and influenza B in 2011.