高海拔地区老年原发性高血压病与2型糖尿病患者动脉硬化程度比较

Comparison of Arterial Stiffness between Patients with Essential Hypertension and Patients with Type 2 Diabetes Mellitus in High Altitude Areas

目的比较高海拔地区老年原发性高血压病与2型糖尿病患者的动脉硬化程度。方法选取我院2012年1—8月收治的老年原发性高血压病患者100例(EH组)和2型糖尿病患者100例(DM组),所有患者年龄>60岁。比较两组患者空腹血糖、总胆固醇、肌酐、糖化血红蛋白水平及臂踝脉搏波传导速度(baPWV)、颈动脉内膜中层厚度(IMT)。结果 EH组空腹血糖、肌酐、糖化血红蛋白水平低于DM组,总胆固醇水平及baPWV〔(10.8±1.3)m/s〕、IMT〔(1.4±0.4)mm〕高于DM组〔(9.3±1.2)m/s,(1.0±0.4)mm,P<0.05〕。结论高海拔地区老年原发性高血压病与2型糖尿病均存在动脉硬化,且原发性高血压病患者动脉硬化程度较2型糖尿病患者严重。

Objective To compare the similarities and differences of arterial stiffness between patients with essential hypertension （EH） and patients with type 2 diabetes meilitus （DM） in high altitude area. Methods 10{3 EH patients （ EH group） and 100 T2DM patients （DM group） over 60 years old admitted to our hospital from January to August 2012 were select- ed. FBG, TC, Cr, HbAl~, baPWV and IMT were compared between the two groups. Results The FBG, Cr and HbA1c in the EH group were significantly lower than those of the DM group, but TC, baPWV ~ （ 10. 8 ~ I. 3） m/s）, IMT [ （ 1. 4 ±0. 4） mm） were significantly higher than the DM group [ （9.3 ~ 1.2） m/s, （1.0 ±0. 4） mm） （P 〈0. 05） . Conclusion Elderly patients with EH or T2DM exist arteriosclerosis, and the arterial stiffness in EH patients is more serious than T2DM patients in high altitude areas.