牛黄清心丸防治小儿热性惊厥疗效观察

Curative Effect Observation of Bezoar Sedative Pill on Preventing and Treating Pediatric Febrile Convulsion

目的:观察牛黄清心丸辅助治疗小儿热性惊厥的疗效。方法:选取热性惊厥患儿60例,随机分为牛黄清心丸治疗组和对照组各30例,两组均给予常规治疗,治疗组加用口服牛黄清心丸(3g/天,3～5天)。出院后所有患儿随访1年。随访期间患儿如再次出现发热,治疗组予口服退热药加牛黄清心丸(3g/天,3～5天),对照组仅口服退热药。比较两组住院期间发热持续时间、出院后1年内各组热性惊厥复发病例数。结果:治疗组患儿住院期间发热持续时间较对照组缩短,两组间比较有统计学意义(P<0.05);随访1年期间,治疗组热性惊厥复发例数低于对照组,两组间比较有统计学意义(P<0.05)。结论:牛黄清心丸辅助治疗可以缩短热性惊厥患儿发热持续时间,并可减少热性惊厥复发例数。

Objective： To investigate the clinical effect of the therapy of Bezoar Sedative Pill on children with febrile convul sion. Methods ： 60 children with febrile convulsion participated in the study. 30 cases were randomly assigned into therapy group （ Bezoar Sedative Pill add conventional therapy） and 30 cases were in controlled group （ conventional therapy）. All patients were followed up for one year after discharge. During follow up, children in treatment group were given oral antipyretics add Be zoar Sedative Pill when they got fever again; while children in controlled group were given oral antipyretics alone when they got fever. Then the time of continued fever during hospital and the eases of recurrent febrile convulsion within one year after discharge were compared between the two groups. Results ： The time of continued fever of patients in therapy group during hospital was significantly shorter than those in controlled group （ P〈O. 05 ）, and the cases of recurrent febrile convulsion in therapy group within one year after discharge was significantly less than recurrent cases in controlled group （ P〈O. 05 ）. Conclusion ： Bezoar Sedative Pill can shorten the time of continued fever during hospital and decreases the cases of recurrent febrile convulsion within one year after discharge.