期刊文献+

损伤控制性复苏对创伤性凝血障碍的影响 被引量:15

Effect of damage control resuscitation on traumatic coagulopathy
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摘要 目的 在创伤早期即采用损伤控制性复苏(damage control resuscitation,DCR)理念,为改善创伤救治进行尝试.方法 2009~2012年我院急救中心收治的严重多发伤患者,86例采用DCR,56例仍按传统复苏方法进行救治.结果 DCR组的死亡率及并发症发生率均明显低于传统复苏组(P〈0.01).结论 对于严重多发伤的患者,应积极实施DCR,可有效地缩短住院时间,减轻创伤应激,快速纠正创伤致死三联征,提高一期确定性手术率,降低严重多发伤病死率. Objective Damage control resuscitation (DCR) is suited to solve this problem during the early treatment period of severe trauma. Methods A retrospective analysis was made on the clinical data with multiple injuries treated from 2009 to 2012. Eigty - six cases of severe multiple injuries were treated by DCR. Fifty - six cases were treated by traditional ways. Results The mortality and complication of DCR were significantly lower than those of traditional ways in the treatment of severe traumas wounded(P 〈 0.01 ). Conclusion Cases of severe muhiple injuries should be treated by DCR actively. DCR can shorten the operating time, lessen the wound response, quickly correct the lethal triad of death, increase the rate of definite operation on first time and lower the mortality of severe multiple injuries.
出处 《中国急救医学》 CAS CSCD 北大核心 2013年第10期901-903,共3页 Chinese Journal of Critical Care Medicine
关键词 损伤控制性液体复苏 创伤性凝血功能障碍 创伤致死三联征 确定性手术 Damage control resuscitation Traumatic coagulopathy Lethal triad of death Definite operation
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参考文献14

  • 1杨帆,白祥军,唐朝晖,李占飞,刘开俊,宋先舟.4519例多发伤院内救治分析[J].中国医学科学院学报,2007,29(4):471-477. 被引量:46
  • 2Mikhali J,et al.The trauma triad of death:hypothermia,acidosisand coagulopathy[J].ACCN Clin Issues,1999,10(1):85-94.
  • 3Bernard F,Lucia R,Alexandre F,et al.Early coagulopathy in trauma patients:An on-scene and hospital admission study[J].Injury,2012,43(1):26-32.
  • 4Sehreiber MA.Damage control surgery[J].Crit Care Clin,2004,20(1):101-118.
  • 5De Waele JJ,Vermassen FE.Coagulopathy,hypothermia and acidosis in trauma patients the rationale for damage control surgery[J].Acta Chir Belg,2002,102(5):313-316.
  • 6Holcomb JB,Jenkins D,Rhee P,et al.Damage control resuscitation:directly addressing the early coagulopathy of trauma[J].J Trauma,2007,62(2):307-310.
  • 7蒋勇,张义胜,赵国海.损伤控制性复苏对家兔急性重度失血性休克的影响[J].皖南医学院学报,2009,28(6):405-407. 被引量:5
  • 8Roberts K,Revell M,Youssef H,et al.Hypotensive resuscitation in patients with ruptured abdominal aortic aneurysm[J].Eur J Vasc Endovasc Surg,2006,31(4):339-344.
  • 9低血容量休克复苏指南(2007)[J].中国实用外科杂志,2007,27(8):581-587. 被引量:233
  • 10黄强,陈自力,李剑.失血性休克大鼠不同血压 时相心脑病理改变的研究[J].中国急救医学,2011,31(3):224-226. 被引量:3

二级参考文献42

  • 1白祥军,裘法祖.建立创伤外科专科 提高多发伤救治水平[J].中华创伤杂志,2004,20(12):709-710. 被引量:50
  • 2文亮,刘明华,熊建琼,任小宝,尹昌林.创伤急救模式的探索[J].中国急救医学,2005,25(1):41-43. 被引量:51
  • 3田利华,胡山而,刘开俊.创伤性死亡危险因素与评价[J].创伤外科杂志,2005,7(2):102-105. 被引量:11
  • 4李喆,华积德.损伤控制外科理念在严重创伤和多发伤救治中的应用[J].中华创伤杂志,2006,22(5):321-323. 被引量:46
  • 5HESS JR, HOLCOMB JB, HOYT DB,et al. Damage control resuscitation : the need for specific blood products to treat the oagulopathy of trauma [ J] . Transfusion,2006,46(5 ) :685 - 686.
  • 6HOLCOMB JB,JENKINS D,RHEE P,et al. Damage control resuscitation: directly addressing the early coagulopathy of trauma [ J ]. J Trauma,2007,62 ( 2 ) :307 - 310.
  • 7KOLLIAS G,DOUNI E,KASSIOUS G,et al. On the role of tumor necrosis factor and receptors in models of muhiple organ failure, rheumatoid arthritis, multiple sclerosisand inflammatory bowel disease[J]. Immunol Rev,1999,169( 1 ) :175 - 194.
  • 8NIMAH M, BRILLI R J. Coagulation dysfunction in sepsis and multiple organ system failure [ J ]. Crit Care Clin,2003,19 ( 3 ) :441 - 458.
  • 9HRISTOVA M, YORDANOV M, IVANOVSKA N. Effect of fangchinoline in murine models of multiple organ dysfunction syndrome and septic shock[J]. Inflamm Res,2003,52( 1 ) :1 -7.
  • 10GIANNOUDIS P V, HILDEBIAND E, PAPE H C. Inflammatory serum markers in patients with multiple trauma:can they predict outcome[J] . J Bone Joint Surg Br,2004,86 (3) :313 -323.

共引文献285

同被引文献147

  • 1任建安,黎介寿.损伤控制性复苏[J].中国实用外科杂志,2007,27(8):593-594. 被引量:52
  • 2Floccard B, Rugeri L, Faure A, et al. Early coagulopa- thy in trauma patients., an on-scene and hospital ad- mission study[J]. Injury, 2012,43 : 26- 32.
  • 3Kirkman E, Watts S, Hodgetts T, et al. A proactive approach to the eoagulopathy of trauma: the rationale and guidelines for treatment[J]. JR Army Med Corps, 2008,153:302-306.
  • 4Maegele M. Coagulopathy after traumatic brain inju ry : incidence, pathogenesis, and treatment options [J]. Transfusion, 2013,53:28-37.
  • 5Niles S E, Mclaughlin D F, Perkins J G, et al. In- creased mortality associated with the early coagulopa- thy of trauma in combat casualties [J]. J Trauma, 2008,64 : 1459- 1463.
  • 6Brohi K,Cohen M J,Ganter M T,et al. Acute coagu-lopathy of trauma: hypoperfusion induces systemic an- ticoagulation and hyperfibrinolysis [J]. J Trauma, 2008,64 : 1211 - 1217.
  • 7Westphal M,James M F,Kozek Langeneker S, et al. Hydroxyethyl starches: different products-different effects[J]. Anesthesiology, 2009,111 : 187 - 202.
  • 8Young P P, Cotton B A, Goodnough L T. Massive Transfusion protocols for patients with substantial hemorrhage[J]. Transfus Med Rev, 2011,25.. 293 - 303.
  • 9Seckin Ulusoy,Oguz Kayiran,Nurhan Ozbaba,et al.Changing strategies in the treatment of maxillofacial fractures at thrace region:open vs closed reduction[J].Oral health and dental management,2014,13(1):8-13.
  • 10M Kit Delgado,Michael A Yokell,Kristan L Staudenmayer,et al.Factors associated with the disposition of severely injured patients initially seen at non–trauma center emergency departments:disparities by insurance status[J].JAMA surgery,2014,149(5):422-430.

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