慢加亚急性肝衰竭胃黏膜病变120例分析

An analysis on 120 cases of gastric mucosa lesions in patients with subacute-on-chronic liver failure

目的观察慢加亚急性肝衰竭患者胃黏膜镜下特点。方法采取回顾性分析,选取慢加亚急性肝衰竭患者120例为研究组,选取慢性肝病100例作为对照,比较胃镜下特点。结果研究组出现多种消化道病变,反流性食管炎44例(37%),胃溃疡30例(25%),糜烂性胃炎61例(51%),门脉高压性胃病24例(20%),胃底静脉曲张37例(31%),与对照组比较,差异有显著性(P<0.05);2级、3级反流性食管炎研究组为33例(75%),中重度浅表性胃炎研究组为78例(82%),急性期溃疡研究组为22例(73%),与对照组比较,差异均有显著性(P<0.05)。HP阳性率两组差异无显著性。结论慢加亚急性肝衰竭患者胃黏膜损害普遍较重,需要积极治疗。

【Objective】To observe endoscopic features of gastric mucosa in patients with subacute-on-chronic liver failure.【Methods】Retrospective analysis was made on 120 patients of subacute-on-chronic liver failure who were involved in study group,and compared the endoscopic features with 100 cases of chronic liver disease in control group.【Results】Occurrence of many kinds of gastric mucosa lesions in patients of study group： 44 cases of reflux esophagitis（37%）,30 cases of gastric ulcer（25%）,61 cases of erosive gastritis（51%）,24 cases of portal hypertensive gastropathy（20%）,37 cases of gastric varices（31%）,there was significant difference between study group and control group and P values were less than 0.05;33 cases of grade 2 and grade 3 of reflux esophagitis cases（75%）,78 cases of mild to severe chronic shallow gastritis（82%）,22 cases of acute gastric ulcer（73%） in study group were significantly different from control group,P values were all less than 0.05.The H.pylori positive rate of two groups had no significant difference.【Conclusions】Gastric mucosa lesions in patients with subacute-on-chronic liver failure are generally heavier,requiring aggressive therapy.